Tuesday, May 11, 2010

'Mouse Grimace Scale' to Help Identify Pain in Humans and Animals

http://www.sciencedaily.com/releases/2010/05/100509144655.htm

This new study will help scientists ensure that laboratory animals don’t suffer unnecessarily and could lead to new and better pain-relief drugs for humans. Mice like human express pain through facial expressions. Through this study they have devolved a Mouse Grimace scale that could inform better treatments and improve the conditions for lab animals.

Pain research relies heavily on rodent models, an accurate measurement of pain is paramount in understanding the most pervasive and important symptom of chronic pain, namely spontaneous pain.

"The Mouse Grimace Scale provides a measurement system that will both accelerate the development of new analgesics for humans, but also eliminate unnecessary suffering of laboratory mice in biomedical research," says Mogil. "There are also serious implications for the improvement of veterinary care more generally."

This is the first success scale that can measure spontaneous responses in animals that resemble human responses to those same painful states.With further research the goal is to see if the scale works equally with all the animals used in labs.


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