Monday, May 16, 2011
Research Uncovers A Biomarker Which Predicts A Relapse in Breast Cancer
Tissue samples are taken from the site of the tumor. Specimens were collected from female breast cancer patients and with 85% accuracy they were able to predict if the patient would have a relapse of breast cancer.
The studies lead researcher Dr. Masoud Manili said " our findings could lead to clinical trials that test whether using immunotherapy prior to conventional treatment in breast cancer patients with a high risk of relapse could prime the patients immune system much like a vaccine, to prevent the liklihood of relapse."
Caffeine Found To Have Helpful Antioxident Properties In Preventing Disease
Scientists are not sure what the correllation between caffeine and these diseases are but know the antioxidents have some value in protecting people from certain diseases. Right now scientists have only come to theoretical conclusions about the effects of caffeine on the prevention of certain diseases. Hopefully further research will discover if there is in fact a way caffeine does in fact prevent the onset of certain diseases.
Stem Cells Show Promising Results in Treatment of Parkinson's Disease
Parkinson's disease is a degenerative disease which results in loss of nerve cells. The current treatments available to patients provide only relief from symptoms but cannot reverse the progression of the disease. It is believed these stem cells will have the ability to regenerate and repair diseased tissue.
This research shows so much promise in the treatment of Parkinson's disease and possibly many other diseases that can potentially be treated with stem cells.
Vitamin D Deficiency Linked to Mortality with Pneumonia
A study was conducted which measured Vitamin D in the blood samples of 112 adult patients admitted to the hospital with pneumonia. The research findings showed higher mortality within the first 30 days after a person was admitted to the hospital. They know that vitamin D is linked to the immune response of a human. They are now looking into the role of Vitamin D and the treatment of pneumonia.
Sunday, May 15, 2011
Wild Fungus
http://www.sciencedaily.com/
Saturday, May 14, 2011
The Future of Beluga Whales and Bottle Nose Dolphins
Hollings Marine Laboratory has stated that, in tests of urbanized waters, Bottle Nose Dolphins and Beluga Whales who are at the top of their food web have had chemical pollutants in their body. Environmental Science and Technology research team looked at the levels of pollutants found in male dolphins along the east coast. Levels of PFC’s (Perflourinated Compounds) have been high in Beluga Whales along the Alaskan Coast. Data gathered in both studies are expected to serve for future research to retrieve the health effects and impacts of these pollutants on the two species.
These chemicals are human made chemicals that spread globally through water and air. These can cause immune and endocrine effects on wildlife and humans. To test for these chemicals in bottle nose dolphins, researchers collect and examine blubber biopsy samples along the East Coast waters. For the Beluga Whales the researchers studied the liver of the whales. All of the Beluga livers had PFC’s in them which was a bad sign of their living conditions.
The testing of these animals will only lead to future safety of endangered species. As well, the testing will provide answers for testing of other animals in the future. With these chemicals increasing in area, the testing is needed and must be done for a solution to this problem.
http://www.sciencenews.org/
Not far from the Arctic Circle, Stone Age tool makers left hard evidence to understand. Artifacts found in this area imply that tool makers worked in frigid conditions. The tools that where discovered where a resemblance of cutting tools, and carpentry tools. The time of when the tools where being formed show that the stone-age was very confined. The settlers that made these tools, kept them to themselves with the older stone-age culture being preserved. Stone-Age tools attributed to modern human societies, which as early as 45,000 years ago, include small rectangular blades and spear points. Ludovic Slimak, the finder of these artifacts, explained that the tools used not only by Stone Age people but by some recent hunter-gatherers to kill and butcher animals. Slimak and his team studied more than 300 stone artifacts and 4,000 animal bones that have been excavated since 1996. The artifacts include cutting tools and large rocks from which they have been removed with pounding stones. Nearly two dozen mammoth, reindeer, and brown bear bones, display butchery marks. This was a huge finding in their study of the exact time of the Stone Age. The way they find how long these artifacts have been buried is by measurements of carbon decay in bones.
Bacterium
Researchers at the Johns Hopkins Bloomberg School of Public Health have identified a bacterium in mosquitoes that stops the development of Plasmodium falciparum, the parasite that causes malaria in humans. According to the study, the bacterium is part of the naturally occurring microbial flora of the mosquito's gut and kills the parasite by producing reactive oxygen species. They have known from past testing that mosquitos mid gut bacteria can be used to limit the malaria parasite. The resent studies have shown that certain bacteria can block the malaria parasites development through the radicals that are detrimental to Plasmodium. "We are particularly excited about this discovery because it may explain why mosquitoes of the same species and strain sometimes differ in their resistance to the parasite, and we may also use this knowledge to develop novel methods to stop the spread of malaria, says George Dimopoulos, of Department of Microbiology. One strategy is to release the mosquito back into its field and to see if the gut can resists the malaria. The future of preventing malaria would be a huge accomplishment, worldwide malaria affects more than 225, million people. Each year this disease kills 800, thousand people, many who are children in Africa. The research to find the solution to lead to the cure would be a future goal for many Scientists.
Thursday, May 12, 2011
Researchers Discover Human Lung Stem Cell
Researchers at Brigham and Women's Hospital have discovered a true human lung stem cell. The human lung stem cell is self-renewing and capable of forming multiple biological structures within the lung.
"These are critical first steps in developing clinical treatment for those with lung diseases for which no therapies exist. Further research is needed, but we are excited about the impact this discovery could have on our ability to regenerate or recreate new lung tissues to replace damaged areas of the lungs," said Joseph Loscalzo, M.D. Phd., chair of the Department of Medicine at BWH and co-author.
As someone who has lost two grandfathers and a father to lung cancer these findings seem promising for the treatment of lung cancer in the future. In the past a diagnosis of lung cancer was a death sentence.
Missing Link for Fungi Found in University Pond
The temporary name for the new group is Cryptomycota that come from the Greek meaning "hidden fungi". Cryptomycota lack a tough cell wall which is crucial for the growth of fungi and how they feed.
Dr. Meredith Jones from the University of Exeter found the microbes . She said " While the first samples used in oir investigation was taken from the univeristy pond, cryptomycota are present in samples taken from all over the world. The huge genetic diversity and prevelence of this group leads us to believe they probably play an important role in a rang of environmental processes."
Warmer Weather Responsible for Increased Prices in Food
Tuesday, May 10, 2011
What Smells? Oh, the World's Smelliest Flower!
The Titan Arum plant, nicknamed the Corpse flower because of its pungent smell of rotting flesh, is in full bloom after 75 years at the University of Basel in Switzerland. According to Bioscholar, the flower was expected to remain open until Easter Sunday.
The eight-foot plant, indigenous to Indonesia’s rain forests, has the largest unbranched shoot in the world. On average, they bloom once in a decade. Collectors and plant enthusiasts around the world desire Titan Arum because of its strange blooming patterns. Twelve of them are housed at the Royal Botanic Gardens, Kew, in the Princess of Wales Conservatory among hundreds of other tropical plants. When the plants are ready to pollinate, the stem heats up to release a pungent smell, which lasts for about three days.
The largest Arum at Kew gardens weighs 200 pounds and grows at a staggering rate of a quarter of an inch an hour. It guzzles liquid fertilizer and potassium each week to keep up its strength while bedded in roomy surroundings. Sir David Attenborough, naturalist and a natural history filmmaker, who invented the name Titan Arum, was the first to capture it flowering on film for his BBC TV series “The Private Life of Plants”. He dropped the plant’s original name – Amorphophallus – perhaps because of the reference to male genitalia.
I could not help but laugh when I read this article. I found it very interesting that a plant could, in fact, smell like rotting flesh. I would have loved to witness this. I also found it rather humorous that it's original name referenced a penis.
Fixated by Screens, but Seemingly Nothing Else
"My child can sit and watch TV for hours, he can’t have A.D.H.D."
In fact, a child’s ability to stay focused on a screen, though not anywhere else, is actually characteristic of attention deficit hyperactivity disorder. There are complex behavioral and neurological connections linking screens and attention, and many experts believe that these children do spend more time playing video games and watching television than their peers.
But is a child’s fascination with the screen a cause or an effect of attention problems — or both? It’s a complicated question that researchers are still struggling to figure out.
According to the New York Times, the kind of concentration that children bring to video games and television is not the kind they need to succeed in school or elsewhere in real life, according to Dr. Christopher Lucas, associate professor of child psychiatry at New York University School of Medicine. “It’s not sustained attention in the absence of rewards,” he said. “It’s sustained attention with frequent intermittent rewards.”
The child may be playing for points accumulated, or levels achieved, but the brain’s reward may be the release of the neurotransmitter dopamine. Children with A.D.H.D. may find video games even more gratifying than other children do because their dopamine reward circuitry may be otherwise deficient. At least one study has found that when children with A.D.H.D. were treated with methylphenidate (Ritalin), which increases dopamine activity in the brain, they played video games less. The authors suggested that video games might serve as a kind of self-medication for these children.
So increased screen time may be a consequence of A.D.H.D., but some researchers fear it may be a cause, as well. Some studies have found that children who spend more time in front of the screen are more likely to develop attention problems later on. In a 2010 study in the journal Pediatrics, viewing more television and playing more video games were associated with subsequent attention problems in both schoolchildren and college undergraduates. The stimulation that video games provide “is really about the pacing, how fast the scene changes per minute,” said Dr. Dimitri Christakis , a pediatrician at the University of Washington School of Medicine who studies children and media. If a child’s brain gets habituated to that pace and to the extreme alertness needed to keep responding and winning, he said, the child ultimately may “find the realities of the world underwhelming, understimulating.”
This article really caught my eye due to the fact that A.D.H.D. is becoming more and more common among children and teens. Sometimes I feel that this so called "disease" is not a disease at all; I feel that it is somewhat of an excuse. That is my personal opinion. I just found it very interesting that kids with A.D.H.D. use television and video games to feel better. I also found a great article with opinions from patients about A.D.H.D.
http://www.nytimes.com/interactive/2008/05/21/health/healthguide/TE_ADHD_CLIPS.html?ref=views
Study Suggests a Relationship Between Migraine Headaches in Children and a Common Heart Defect
Roughly 15% of children suffer from migraines, and approximately one-third of these affected children have migraines with aura, a collection of symptoms that can include weakness, blind spots, and even hallucinations. According to ScienceDaily, although the causes of migraines are unclear, a new study in The Journal of Pediatrics suggests a connection between migraine headaches in children and a heart defect called patent foramen ovale, which affects 25% of people in the U.S.
Dr. Rachel McCandless and colleagues from the Primary Children's Medical Center and the University of Utah studied children 6-18 years old who were diagnosed with migraines between 2008 and 2009. The researchers took two-dimensional echocardiograms (sonogram of the heart) of each child's heart, looking for a patent foramen ovale (PFO), a common defect in the wall between the two upper chambers of the heart. Although a PFO is not necessarily dangerous, it can allow unfiltered blood to bypass the lungs and circulate throughout the body. As Dr. McCandless explains, "Some adult studies have suggested a link between having a PFO and migraine headaches."
Of the studied children who had migraines with aura, 50% also had a PFO; this is nearly double the PFO rate of the general population. However, only 25% of children who had migraines without aura had a PFO. Dr. McCandless and colleagues hypothesize that if a causal relationship can be established, closure of a PFO with a catheter device may help in the treatment of certain kinds of migraines, specifically migraines with aura. It is her hope that "our study will help guide future research about this difficult problem."
I chose this article due to the fact that a close friend of mine suffers from migraines. It is terrible to see what she has to go through when she has a migraine. She has them so bad that she sometimes ends up vomiting from the pain. I thought it was really interesting how they related migraines to a heart defect. Who would've thought something wrong with the heart could cause pain in your head?
Monday, May 9, 2011
Scientists Find Five New Alzheimer's Risk Genes
Sunday, May 8, 2011
Genetics May Personalize Quit-Smoking Methods
Study Uncovers Genes That Aid Malarial Resistance
Study: Genetic Link Found Between Prostate, Womb Cancers
Season of Birth May Affect the Rest of Your Life
Pesticide exposure in womb may hurt your child's IQ
Waist size predicts heart-disease death better than weight
Friday, May 6, 2011
Box Jellyfish Have Eyes, Allowing it to See the World Above
Sea Squirts and Starfish and Eternal Life? Oh My!
Protein Keeps Sleep-Deprived Flies Ready to Learn
Giant fossil ants linked to global warming
Selaginella genome adds piece to plant evolutionary puzzle
US removes gray wolf from endangered list
Thursday, May 5, 2011
Prolonged Bottle Feeding Increases the Risk of Obesity
http://www.sciencedaily.com/releases/2011/05/110505083116.htm
http://www.us.elsevierhealth.com/home.jsp?sgCountry=US&sgCountry=US
Experts agree that obesity prevention should begin before children enter school. A new study soon to be published in The Journal of Pediatrics suggests that limiting long term bottle use in children may be an effective way to help prevent obesity. Dr. Robert Whitaker and Dr.Rachel Gooze analyzed data from 6750 children to estimate the association between bottle use at 24 months of age and the risk of obesity at 5.5 years of age.
Of the children studied, 22% were prolonged bottle users. At 2 years of age they used a bottle as their primary drink container and/or were put to bed with a calorie-containing bottle. Nearly 23% of the prolonged bottle users were obese by the time they were 5.5 years old. "Children who were still using a bottle at 24 months were approximately 30% more likely to be obese at 5.5 years, even after accounting for other factors such as the mother's weight, the child's birth weight, and feeding practices during infancy," Dr. Whitaker notes.
Drinking from a bottle beyond infancy may contribute to obesity by encouraging the child to consume too many calories. "A 24-month-old girl of average weight and height who is put to bed with an 8-ounce bottle of whole milk would receive approximately 12% of her daily caloric needs from that bottle," Rachel Gooze explains. She notes that weaning children from the bottle by the time they are 1 year of age is unlikely to cause harm and may prevent obesity. The authors suggest that pediatricians and other health professionals work with parents to find acceptable solutions for stopping bottle use at the child's first birthday.
I found this article to be very interesting, it will definitely make me think twice about feeding my future children from a bottle, even before the 24 month mark. I know not all mothers have the ability to Brest feed but this may make them think twice about that option. Brest feeding eliminates the difficult task of weaning a child off a bottle, and if you skip the bottle all together and go right to a sippy cup or only break out a bottle when it's absolutely necessary (like if you had to leave a Brest feeding baby with a sitter for a few hours) it makes it easier to eliminate them and you would be decreasing your child's risk for obesity. I personality don't think baby's should go to bed with a bottle, to me that's like asking them to be over weight. Just like adults shouldn't eat right before bed because the calories have no where to go and they just sit in your body all night and contribute to weight gain, so I think that concept makes perfect sense. I think is article gives good insight to an issue many parents aren't aware of.
Renewable Energy
Hope for the Cure of Common Eye Diseases.
A Possible Cure for Baldness?
Turning 'Bad' Fat into 'Good' Fat
More than two-thirds of adults in the United States are overweight, and more than one-third are obese, according to government estimates.
According to ScienceDaily, by knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.
"If we could get the human body to turn 'bad fat' into 'good fat' that burns calories instead of storing them, we could add a serious new tool to tackle the obesity epidemic in the United States," says study leader Sheng Bi, M.D., an associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.
The Johns Hopkins study, published in the journal Cell Metabolism, looks at two types of fat made by the body: white and brown adipose tissue. White fat is the typical fat that ends up around your middle and other places, and is the storehouse for the extra calories we eat. White fat cells have a single large droplet of lipid, one of fat's building blocks, such as cholesterol and triglycerides.
Bi and his colleagues designed an experiment to see if suppressing the appetite-stimulating neuropeptide Y (NPY) protein in the dorsomedial hypothalamus of the brain would decrease body fat in rats. Located just above the brain stem, the hypothalamus helps regulate thirst, hunger, body temperature, water balance and blood pressure.
For five weeks, two groups of rats were fed a regular diet, with one group also treated with a virus to inhibit NPY expression and the other left as a control group. At the end of five weeks, the treated group weighed less than the control group, demonstrating that suppression of NPY reduced eating.
Then, researchers split each of the groups into two, creating four sets of rats. One of the treated groups of rats and one of the control groups were fed a regular diet while the other treated and control groups got a high-fat diet. Of the rats on the regular diet, the control group weighed more at the end of 11 weeks than those rats in which hypothalamic NPY expression was knocked down. In the high-fat group, the control group rats became obese; those rats in which NPY expression was silenced gained less weight.
Bi says he believes that the transformation from white to brown fat resulting from NPY suppression may be due to activation of brown fat stem cells contained in white fat tissue. While brown fat seems to vanish in humans as they emerge from infancy, the brown fat stem cells may never disappear and may just become inactive as people age.
Bi says it may be possible to transplant or inject brown fat stem cells under the skin to burn white fat and stimulate weight loss. "Only future research will tell us if that is possible," he says. This study also shows that low levels of hypothalamic NPY increase spontaneous physical activity, improve blood sugar levels and enhance insulin sensitivity in rats, but it remains undetermined whether this brown fat transformation also contributes to these effects.
I found this article to extremely interesting. You cannot go a day without hearing about obesity on the news. I feel that this research can lead to a better, more natural way to help those who are obese lose weight.
Wednesday, May 4, 2011
How to Communicate with an Alzheimer's Patient
The best form of communication is validation. Everyone wants their feelings validated, especially AD patients. If their feelings aren't validated, they will feel angry and upset. Remind them of old memories as well.