Sunday, October 25, 2009

Brief shocks may deliver AIDS vaccines better

Brief electric shocks may help the body better respond to certain kinds of experimental AIDS vaccines. Sandhya Vasan of the Aaron Diamond AIDS Research Center in New York said the technique, called electroporation, may be particularly useful in delivering DNA vaccines, which use an infectious agent's own genetic material to elicit an immune response.

The brief shock temporarily opens up the cell membrane and allows a lot more of the DNA to get inside. When the vaccine was given by injection alone, only 25 percent of participants developed any immune response. But in its latest trial in 2007-2009 when the same vaccine was delivered using electroporation, the immune response appeared far stronger, Vasan told a meeting of AIDS vaccine researchers in Paris.

http://www.newsdaily.com/stories/tre59l4sv-us-aids-vaccine-electricity/

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